Pain

Peripheral Vascular Disease

Peripheral vascular disease (PVD) is the narrowing of the arteries, and obstruction of blood flow to the limbs. People often have leg pain, cramping, or muscle pain in the arms or legs from walking, or other physical activities. The pain might disappear after a few minutes of rest depending on the severity and location of the clogged artery. Other symptoms might include arm, leg, hand, and foot numbness, weakness, coldness, sores or discoloration, hair and toenail loss, or slow growth, shiny leg skin, a weakened pulse, and erectile dysfunction for men.
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Peripheral vascular disease is often caused by fatty deposit (plaques) that build up in the artery walls and restrict blood and oxygen flow to the limbs. Blood vessel inflammation, limb injuries or deformities, or radiation exposure can also lead to the onset of the disease.

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Source: Mayo Clinic
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